I have the same problem mentioned earlier; but as it was last year, and there are still no answers, here it is:

The program will appear to start normally, but the first time I click on it, it hangs. The full error message reads as follows:

Description:
A problem caused this program to stop interacting with Windows.

Problem signature:
Problem Event Name: AppHangB1
Application Name: TMPGEncKarmaPlus.exe
Application Version: 1.0.2.30
Application Timestamp: 4af784a9
Hang Signature: d169
Hang Type: 256
OS Version: 6.1.7600.2.0.0.768.3
Locale ID: 1033
Additional Hang Signature 1: d16977bb1731751c618f8f6d900c4bf9
Additional Hang Signature 2: 3232
Additional Hang Signature 3: 3232786cdaef5a0603c843eaff67fe63
Additional Hang Signature 4: d169
Additional Hang Signature 5: d16977bb1731751c618f8f6d900c4bf9
Additional Hang Signature 6: 3232
Additional Hang Signature 7: 3232786cdaef5a0603c843eaff67fe63

This was advertised as working with Win 7. Not so?

I would also like Karma to export playlists to Authoring Works 4 so they are ready to burn!

I would like the ability to move and delete files from my system within Karma!

It would be sooo cool if Karma played DVD's!

I would like a setting to keep the player on top of all windows. Surely this is a must!

Anyone try this? It definitely seems better than the free version. I like the video comparison feature. It feels like iTunes for your video files. I wish there was H.264 output for people who don't have CUDA though.

Yes, I have bought it, installed it, but won't start ! I have tried many times re-installation. I have good PC and my os is Windows 7. Have alle updated drivers.
The "light" version of the program works fine, but TMPGEnc KARMA..Plus won¨'t start. Have sent for support-help, but no helps.

I've installed trial version of TMPGEnc KARMA..Plus (TMKP_Trial_1.0.2.30_setup_en.exe) but I failed to launch the application.
I tried to launch it on PC having the following configuration:
Windows 7
Core 2 Duo E8400, 2Gb RAM, ASUS P5K-E/WiFi, MSI 8800GT 512Mb
My PC was connected to Internet.
I got a message that application was stopped and here is detailed information:
Name of the problem: APPCRASH
Application Name: TMPGEncKarmaPlusTrial.exe
Application Version: 1.0.2.30
Application Timestamp: 4af784eb
Fault Module Name: KERNELBASE.dll
Fault Module Version: 6.1.7600.16385
Fault Module Timestamp: 4a5bdaae
Exception Code: e053534f
Exception Offset: 00009617
OS version: 6.1.7600.2.2.0.256.1
Language code: 1049

I have much of the same problems! I tried the free version first and was happy with this, so I wanted the extra features in the full version. I even checked the Compatibility Chart to see wether Win7 64-bit was supported, and it was supposed to, but nothing happens when I try to open the program. This is rally a bad thing now that the jump to 64-bit versions is here with Win7...!